KEGG   Homo sapiens (human): 747
Entry
747               CDS       T01001                                 
Symbol
DAGLA, C11orf11, DAGL(ALPHA), DAGLALPHA, NSDDR
Name
(RefSeq) diacylglycerol lipase alpha
  KO
K13806  sn1-specific diacylglycerol lipase [EC:3.1.1.116]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04723  Retrograde endocannabinoid signaling
hsa04925  Aldosterone synthesis and secretion
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    747 (DAGLA)
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    747 (DAGLA)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.116  sn-1-specific diacylglycerol lipase
     747 (DAGLA)
SSDB
Motif
Pfam: Lipase_3
Other DBs
NCBI-GeneID: 747
NCBI-ProteinID: NP_006124
OMIM: 614015
HGNC: 1165
Ensembl: ENSG00000134780
UniProt: Q9Y4D2
Position
11:61680391..61747001
AA seq 1042 aa
MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR
GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT
QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY
NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL
VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFAL
AAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLD
ENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVE
GHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAI
LSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQ
LLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEVTTLASTRLWTHPSDLTIALSASTPLY
PPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLN
KVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRN
SSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQERLAAELQARRAPLATM
ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTEL
LAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELALHNG
RLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILL
RAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIR
TSTPTGHGASPAKQDELVISAR
NT seq 3129 nt   +upstreamnt  +downstreamnt
atgcccgggatcgtggtgttccggcggcgctggtctgtgggcagtgatgacctcgtccta
ccggccatcttcctctttctcctgcataccacctggtttgtgatcctgtccgtggtgctc
ttcggcctggtctataacccgcacgaggcctgctccctgaacctggtggaccacggccgc
ggctacctgggcatcctgctgagctgcatgatcgctgagatggccatcatctggctgagc
atgcgcgggggcatcctctacacggagccccgtgactccatgcagtacgtgctctacgtg
cgcctggccatcctggtgatcgagttcatctacgccatcgtgggcatcgtctggctcact
cagtactacacctcctgcaacgacctcactgccaagaatgtcaccctcggaatggttgtc
tgcaactgggtagtcatcctcagtgtgtgcatcactgtcctctgcgtcttcgaccccacg
ggccgcacctttgtcaagctgagagccaccaagaggaggcagcgtaacctgcggacctac
aacctgcggcaccgcttagaggagggtcaagccaccagctggtcgcgccggctcaaagtg
ttcctctgctgcacgcggacgaaggactcccagtcagatgcctactcagaaatcgcctac
ctctttgcggagttcttccgggaccttgacattgtgccatccgacatcattgctggcctg
gtgctgctccggcagcggcagcgggccaagcgcaacgccgtgctggacgaggcaaacaat
gacatcttggccttcctgtctgggatgccggtgaccagaaacaccaagtacctcgacctc
aagaattcacaagagatgctccgctacaaagaggtctgctactacatgctctttgccctg
gctgcctacgggtggcccatgtacctgatgcggaagcccgcctgcggcctctgccaactg
gctcggtcctgctcgtgttgcctgtgtcctgcgaggccgcggttcgcccctggagtcacc
atcgaggaagacaactgctgtggctgtaatgccattgccatccggcgccacttcctggac
gagaacatgactgcggtggacatcgtctatacctcctgccatgatgcggtctatgaaacg
cccttctacgtggcggtggaccatgacaagaagaaagtggtgatcagtatccgggggacc
ctgtcccccaaggatgccctgactgacctgacgggtgatgctgagcgcctccccgtggag
gggcaccacggcacctggctgggccacaagggtatggtcctctcagctgagtacatcaag
aagaaactggagcaggagatggtcctgtcccaggcctttgggcgagacctgggccgcgga
accaaacactacggcctgattgtggtgggccactccctgggcgcgggcactgctgccatc
ctctccttccttctgcgcccacagtatccgaccctcaagtgctttgcctactccccgcca
gggggcctgctgagtgaggatgcgatggagtattccaaggagttcgtgactgctgtggtt
ctgggcaaagacctcgtccccaggattggcctctctcagctggaaggcttccgcagacag
ctcctggatgtcctgcagcgaagcaccaagcccaaatggcggatcatcgtgggggccacc
aaatgcatccccaagtcggagctgcctgaggaggtagaggtgaccaccctggccagcacg
cggctctggacccaccccagcgacctaactatagccctctcagccagcactccactctac
ccgcccggccgcatcatccacgtggtccacaaccaccctgcagagcagtgctgctgctgt
gagcaggaggagcccacatactttgccatctggggcgacaacaaggccttcaatgaggtg
atcatctcgccagccatgctgcatgagcacctgccctatgtggtcatggaggggctcaac
aaggtgctggagaactacaacaaggggaagaccgctctgctctctgcagccaaggtcatg
gtgagccctaccgaggtggacctgactcctgagctcatcttccagcagcagccactcccc
acggggccgcccatgcccactggccttgccctggagctgccgactgcagaccaccgcaac
agcagcgtcaggagcaagtcccagtctgagatgagcctggagggcttctcggaggggcgg
ctgctgtcgccagtggttgcggcggcggcccgccaggacccggtggagctgctgctgctg
tctacccaggagcggctggcggcggagctgcaggcccggcgggcaccactggccaccatg
gagagcctctcggacactgagtccctgtacagcttcgactcgcgccgctcctcaggcttc
cgcagcatccggggctcccccagcctccacgctgtgctggagcgtgatgaaggccacctc
ttctacattgaccctgccatccccgaggaaaacccatccctgagctcgcgcactgagctg
ctggcggccgacagcctgtccaagcactcacaggacacgcagcccctggaggcggccctg
ggcagtggcggcgtcactcctgagcggccccccagtgctgcggccaatgacgaggaggaa
gaggttggcggtgggggtggcgggccggcctcccgcggggagctggcgctgcacaatggg
cgcctgggggactcgcccagtcctcaggtgctggaattcgccgagttcatcgacagcctc
ttcaacctggacagcaagagcagctccttccaagacctctactgcatggtggtgcccgag
agccccaccagtgactacgctgagggccccaagtcccccagccagcaagagatcctgctc
cgtgcccagttcgagcccaacctggtgcccaagcccccacggctctttgccggctcagcc
gacccctcctcgggcatctcactctcgccctccttcccgctcagctcctcgggtgagctc
atggacctgacgcccacgggcctcagtagccaggaatgcctggcggctgacaagatccgg
acttctacccccactggccacggagccagccccgccaagcaagatgagctggtcatctca
gcacgctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (26)   
   RefSeq(nuc) (12)   
   GenBank (7)   
   EMBL (7)   
Protein domain (1)   
   Pfam (1)   
All databases (65)   

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